Protean 600+ is a latest generation comprehensive genomic profiling test, that uses a single tumor specimen to evaluation over 600 genes.
The Protean 600+ test is part of the Protean MAPS® system, and is designed to provide the most comprehensive information regarding actionable targets in a specimen.
Protean 600+ is helpful in the identification of approved treatments and clinical trial opportunities.
patients to approved treatments and clinical trial opportunities. The test can be used for any cancer type but is ideal for analysis of solid tumors such as breast, lung, colon, pancreas, prostate, sarcoma, and others.
Protean 600+ Highlights:
Evaluates both DNA & RNA, and detects key gene fusions: ALK, RET, ROS, NTRK1,2,3, etc.
Uncovers SNP mutations, deletions, fusions, and copy number variants
Measures microsatellite instability (MSI) and tumor mutational burden (TMB)
Includes key inherited cancer genes
Can uncover important germ line variants
Uses a small amount of FFPE Materials
Detection of exon skipping, alternative splicing, and gene amplifications
The Protean 600+ report provides the information you need in a clear and easy to understand format.
Treatment recommendations organized by level of priority
Clinically actionable results
Potential clinical trials
MSI stability, TMB level
Key gene amplifications and fusions
Ordering Process:
Complete the CNS test requisition form
Send the completed test requisition form via fax or Protean’s secure electronic portal
Ship tissue or slides with pathology report to Protean’s laboratory
Receive results within 5-10 business days
Sample Requirements:
FFPE tissue block or 20 unstained slides.
Overnight shipping required for tissue blocks.
Regular shipping for slides.
Details for slides: 5 micron thick sections, unstained & unbaked, 25 mm² (if less than this size, please provide additional slides), H&E optional
The test can be used for any cancer type but is ideal for analysis of solid tumors such as breast, lung, colon, pancreas, prostate, sarcoma, and others.

The Protean MAPS® System
Methylation Profiling is part of Protean’s full molecular analysis system for CNS tumors.
Protean MAPS® includes Methylation, pathology review, IHC, rapid IDH1/2 mutation testing, NGS profiling and complex fusion analysis
Order Methylation Testing
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